Agricultural Science Euro-North-East

Scientific journal
of the North-East Regional Agricultural Scientific Centre

Phone (8332) 33-10-43
(8332) 33-07-21
Fax: (8332) 33-10-25
Address: Kirov, Lenin's street, 166-a
E-mail: agronauka-esv@fanc-sv.ru

Therapeutic efficacy of ozonated emulsion in acute endometritis in cows-heifers

Pages: 43-49.

Nikolaev S.V., postgraduate student

Vyatka State Agricultural Academy, Kirov, Russia

E-mail: info@vgsha.info

Modern state of dairy cattle breeding is characterized by the growth of milk productivity of cows and increase the incidence of obstetric pathology. The heifer cows with acute endometritis in the contents of the uterus microorganisms are present in the form of monocultures (Proteus vulgaris, Escherichia сoli, Pseudomonas аeruginosa, Еnterobacter faecalis, Staphylococcus аureus, Proteus mirabilis) (75,7%) or in Association (E. сoli + Candida albus, E. coli + Penicillium) (8%). Emulsion consisting of genedicine, fish oil and TWIN 80, subjected to bubbling ozone-oxygen mixture, has antibacterial properties against hemolytic  Escherichia сoli и Staphylococcus аureus. The introduction into the uterine cavity of ozonized emulsion for sick cows postpartum acute endometritis by 35.2% increases therapeutic efficacy, 0.9 times reduces the number of intra-uterine injections, kt 182.8 ml saves the amount of therapeutic agent that has a positive effect on the reproductive system, at 25.8 days reduces the period of existence of the first stage of excitation of sexual cycle after calving and with 82.2 days period from the birth to subsequent pregnancy, reduces the insemination index of cows on average to 1.3. The recovery of the cows is accompanied by a reduction in blood AST activity and ALT, increased levels of total protein and activity of the synthesis of γ – globulin. Indicators of alkaline phosphatase and dynamics of calcium and phosphorus showed the stabilization of mineral metabolism.

Keywords: cows-heifers, endometritis, ozonated emulsion

References

1. Konopel'tsev I.G. Ozonoterapiya i ozono-profilaktika vospalitel'nykh zabolevaniy i funktsional'nykh rasstroystv matki u korov : avtoref. dis. ... d-ra vet.nauk. [Ozone and ozone prophylaxis of inflammatory diseases and functional disorders of the uterus in cows : author. dis. ... Dr. vet.Sciences]. Voronezh, 2004. 40 p.
2. Inozemtsev V.P. Akushersko-ginekologicheskie bolezni u korov v sel'khozpredpriyatiyakh Rossii. [Of obstetric-gynecological diseases in cows on the farms of Russia]. Itogi i perspekt. nauch. issled. po problemam patologii zhivotnykh i razrabotke sredstv i metodov terapii i profilaktiki. Mater. koordinats. soveshchaniya. [Results and perspectives. scientific. issled. on problems of pathology of animals and the development of means and methods of therapy and prevention. Mater. coordination. meeting]. Voronezh, 1995. pp.254.
3. Turchenko A.N. Etiologiya i lechenie poslerodovogo endometrita korov. [The etiology and treatment of postpartum endometritis of cows]. Veterinariya. 2001. no. 7. pp. 33-37.
4. Krotov L.N. Rol' mikrobnogo i gribkovogo faktorov v etiologii i razvitii poslerodovykh zabolevaniy u korov. [Role of microbial and fungal factors in the etiology and development of postpartum diseases in cows]. Agrarnaya nauka Evro-Severo-Vostoka. 2011. no. 2. pp. 58-61.
5. Il'inskiy E.V., Agafonychev V.A., Krokhin A.Ya. Ob usovershenstvovanii lechebno-profilakticheskikh meropriyatiy pri nespetsificheskikh metritakh u korov. [On the improvement of preventive measures with non-specific metritis in cows]. Effektivnost' vet. meropriyatiy v promyshlennom zhivotnovodstve Kubani: Tr. Kubanskogo GAU. [The effectiveness of vet. activities in the livestock industry of Kuban, Proc. Kuban state agrarian UNIVERSITY]. Krasnodar, 1991. Iss. 319. pp. 5-10.
6. Shabunin S.V., Nezhdanov A.G. Sistemnoe reshenie problemy sokhraneniya vosproizvoditel'noy sposobnosti i produktivnogo dolgoletiya molochnogo skota. [Systemic solution to the problem of preserving reproductive capacity and productive longevity of dairy cattle]. Sovremennye probemy veterinarnogo akusherstva i biotekhnologii vosproizvedeniya zhivotnykh. Mater. Mezhdunar. nauch.-prakt. konf., posvyashch. 85-letiyu so dnya rozhdeniya prof. G.A. Cheremisinova i 50-letiyu sozdaniya Voronezhskoy shkoly veterinarnykh akusherov. [Modern. Probl. veterinary obstetrics and biotechnology reproduction of animals. Mater. Intern. scientific.-practical. Conf. devoting to research and development. The 85th anniversary since the birthday of Professor G. A. Cheremisinova and the 50th anniversary of the establishment of the Voronezh school of veterinary obstetricians]. Voronezh, 2012. pp. 10-20.
7. Mikhaylov N.N., Luchko M.A., Konnova Z.S. Poluchenie prob tservikal'noy slizi ot korov. [Obtaining samples of cervical mucus from cows]. Veterinariya. 1967. no. 1. p. 80.
8. Kratkiy opredelitel' bakteriy Bergi. [Concise determinant of Bergy's bacteria]. Moscow, 1980. 496 p.
9. Kartashova V.M., Ivashura A.I. Mastity korov. [Mastitis cows]. Moscow: Agropromizdat, 1988. 256 p.
10. Atlas gribov, patogennykh dlya sel'skokhozyaystvennykh zhivotnykh i ptits. [Atlas of fungi, pathogenic to farm animals and birds]. Moscow: State publishing house of agricultural literature, 1953. 160 p.
11. Sidorov M.A., Skorodumov D.I., Fedotov V.B. Opredelitel' zoopatogennykh mikroorganizmov. [Determinant zoopathogenic microorganisms]. Moscow: Kolos, 2005. 319 p.
12.  Metodicheskie ukazaniya po diagnostike, terapii i profilaktike bolezney organov razmnozheniya u korov i telok». [Guidelines on the diagnosis, therapy and prevention of diseases of the organs of reproduction in cows and heifers]. Moscow, 2000. 68 p.