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• Systematic approach to the development

Systematic approach to the development of methods of prevention of gastro-intestinal diseases in newborn calves

Pages: 46-50.

Burova O.A., Researcher,
Blokhin A.A., PhD. In Veterinary Medicine, Senior Researcher

Scientific and Research Veterinary Institute of the Non-Chernozem Zone of the Russian Federation, Nizhny Novgorod, Russia

E-mail: nivinzrf@mail.ru

The main condition for the prevention of diseases in calves in early postnatal period is the formation of an optimal immunological status of cows-mothers, provision of colostral immunity and colonization resistance of mucous membranes in newborn calves. Methods of prevention of gastro-intestinal diseases should be based on the key   provisions on the system “mother-fetus-newborn”. Our methods includes improving the immune status of different age groups of cattle population united in the system “mother-fetus-newborn” and consists of two stages. In the first stage pregnant cows three months before calving are given the remedy “Immoveton-Ks” at a dose 0f 52.5 mg/kg BW. Then 2 months before calving cows are immunized with vaccine “Hiprobovis-4” at a dose of 3 ml with a booster after 21-30 days. In the second stage newborn calves are given combination of some remedies: “Immoveton-Ks” intramuscularly or subcutaneously at a dose of 52.5 mg /kg BW once daily on day 1, 2 and 7 of life; fermented milk product “EM-Kurunga” orally at a dose of 150 ml from the second day of life 3 times a day for 10 days; Multivitamin + Minerals intramuscularly at a single dose of 1.5 ml on day 8 of life. It is established that immunization with the vaccine “Hiprobovis-4” against the background of correction of the immune status using “Immoveton-Ks” provides for the production of the greatest quantity of specific antibodies. This indicates pronounced stimulating effects of immunomodulator “Immoveton-Ks” on the formation of post-vaccination immunity. Preventive effectiveness of the proposed method on farms with high prevalence of gastrointestinal diseases of calves was 90.5%, the safety – 98.9%, average daily weight gain - 840g.

Keywords: calves, diseases of the digestive apparatus, prevention, system “mother-fetus-newbrn”

References

1. Gladkova N.A. Bolezni telyat v rannem postnatal'nom periode: Avtoref. diss… kandidata vet. nauk. [Diseases in calves in early postnatal period: Author’s abstract of PhD thesis]. Sankt-Peterburg, 2000. 22 p.
2. Ozdemirov A.A., Anaev M.S., Aygubova S.A., Ramazanova D.M. Zheludochno-kishechnye bolezni molodnyaka krupnogo rogatogo skota v prikaspiyskom regione Rossii. [Gastrointestinal diseases in young cattle in the Caspian region of Russia]. Veterinarnaya patologiya. 2013. no. 2. pp. 19-21.
3. Filimonov D.N. Effektivnost' kompleksnogo primeneniya antibiotika na osnove tsiprofloksatsina i apramitsina s probiotikom metabolitnogo tipa pri zheludochno-kishechnykh zabolevaniyakh telyat. [Effectiveness of combined use of antibiotic based on ciprofloxacin and apramycin with probiotic of metabolite type at gastrointestinal diseases in calves]. Voprosy normativno-pravovogo regulirovaniya v veterinarii. 2016. no. 2. pp. 61-65.
4. Isaev V.V., Kosorlukova Z.Ya., Khrisanfova T.D., Korobova O.V. e. a. Korrektsiya immunodefitsitov dlya profilaktiki zheludochno-kishechnykh bolezney novorozhdennykh telyat. [Correction of immunodeficiencies for prevention of gastrointestinal diseases in calves]. Veterinarnaya patologiya. 2005. no. 4. pp. 113-116.
5. Sisyagina E.P., Redzhepova G.R., Sisyagin P.N. Novye sposoby korrektsii immunodefitsitov u telyat. [New methods for correction of immunodeficiencies in calves]. Veterinarnyy vrach. 2009. no. 6. pp. 39-42.
6. Shakhov A.G., Retskiy M.I., Mas'yanov Yu.N., Zolotarev A.I. i dr. Povyshenie effektivnosti spetsificheskoy profilaktiki faktornykh infektsiy putem korrektsii antioksidantnogo i immunnogo statusa korov i telyat. [Enhancing effectiveness of specific prophylaxis of factory infections by correction of antioxidant and immune status of cows and calves]. Veterinarnyy konsul'tant. 2008. no. 23-24. pp. 7-11.
7. Volkova S. Immunnyy status korov i ikh potomstva. [Immune status of cows and their offspring]. Veterinariya sel'skokhozyaystvennykh zhivotnykh. 2011. no. 11. pp. 26-27.
8. Khusainov R.F. Kolostral'nyy immunitet i vnutriutrobnoe infitsirovanie telyat virusom leykoza ot korov-materey s razlichnoy stepen'yu vyrazhennosti infektsionnogo protsessa: Avtoref. diss…. kandidata biol. nauk. [Colostral immunity and intrauterine infection of calves with bovine leukemia virus from cows-mothers with various severity of the leukemic process: Author’s abstract of PhD thesis]. Ufa. 2009. 22 p.
9. Grigor'eva G.I., Arbuzova A.A., Kul'chitskaya M.A., Panitkov M.A. Rol' mikroorganizmov (bakteriy i virusov) v vozniknovenii zheludochno-kishechnykh zabolevaniy novorozhdennykh telyat. [Role of microorganisms (bacteria and viruses) in occurrence of gastrointestinal diseases in newborn calves]. Veterinarnaya patologiya. 2005. no. 4. pp. 108-113.
10. Gumerov V.G. Diagnostika i spetsificheskaya profilaktika respiratornykh i zheludochno-kishechnykh infektsiy krupnogo rogatogo skota: Avtoref. diss…. doktora vet. nauk. [Diagnosis and specific prophylaxis of respiratory and gastrointestinal infections in cattle: Author’s abstract of DSc Thesis]. Kazan', 2016. 34 p.
11. Erina T.A. Mikrobiotsenoz kishechnika i immunnyy status novorozhdennykh telyat s raznym morfofunktsional'nym razvitiem i ikh korrektsiya: avtoref. diss…. kandidata vet. nauk. [Intestinal microbiozinosis and immune status of newborn calves with various morphofunctional development and its correction: Author’s abstract of PhD Thesis]. Voronezh, 2015. 23 p.
12. Plokhinskiy N.A. Algoritmy biometrii. Pod red. akad. AN USSR B. V. Gnedenko. [Algorithms of biometrics. Under the editorship of B.V.Gnedenko]. Moscow: Izd-vo Mosk. gos. un-ta, 1980. 150 p.