Features of of metabolic indicators in pregnant cows during late prenatal period
Pages: 48-53.
Sokolova O. V., PhD in Biology, Senior Researcher
Isakovа M.N., PhD in Veterinary Medicine, Senior Researcher,
Ryaposova M.V., DSc in Biology, head of laboratory
Ural Scientific Research Veterinary Institute, Yekaterinburg, Russia
E-mail: info@urnivi.ru
The article presents data on the study of the characteristics of the biochemical profile in pregnant cows at late gestation. The research was carried out in agricultural organizations of the Sverdlovsk Region. Deviations of mean values of globulin content (47.0±1.2 g/l), total creatine phosphate kinase (310.1±55.4 U/l), triglycerides (0.4±0.1 g/l), magnesium (1.3±0.1 mmol/l) in the group of deep-bodied cows were in the direction of increase in indices. An increase in the total protein content of more than 82 g/l was observed in 37.2% of the cows examined, a decrease in the albumin concentration of less than 29 g/l in 13.2%, a urea level of less than 2.0 mmol / L in 20.7% and aminotransferases (ALT And ASAT) in 1.0…23.1% of deep-bodied cows, respectively. The revealed changes indicate a decrease in the processes of transamination and synthetic function of the liver, due to an increased functional load on the organ. A change in lipid metabolism was revealed, which manifested by an increase in cholesterol content of more than 5.0 mmol/l in 6.0% and triglycerides in 1.5…2 times in 25% of pregnant cows. The increase in activity of creatine phosphate kinase (CK) above 280 U/l was found in 16.9% of pregnant cows, which indicates an increase in the alakta mechanism of energy supply, and may be associated with a pronounced load on the cardiovascular system, an increase in the activity of CK in the placenta in its pathology. A physiological increase in lactate dehydrogenase and alkaline phosphatase was noted in 9.2% and 2.5% of the cows examined, respectively. There is metabolic change in acid-alkaline and water-electrolitic exchanges. At analysis of mineral metabolism indices it was pointed out decrease in calcium and phosphorus content in blood of 9.1 and 15.7 pregnated cows that is linked with increase in processes of ossification of embrion steleton and established of its haemopoesis. Hypokaliemie is recorded in 54.5% of cows. Analysis of results about content of microelements in blood of pregnated cows showed the increase in Zn and Cu content at 10.3 and 4.2% of animals. At this the deficite of these elements was indicated in 6.9 and 8.3% of cows.
Keywords: pregnant cows, biochemical parameters, prenatal period, metabolic disorders
References
1. Babuhin S.N., Avdeenko V.S., Kaljuzhnyj I.I. e.a. Narushenie metabolicheskih processov v organizme beremennyh korov pri razvitii subklinicheskogo ketoza. [Violation of metabolic pro-cesses in the organism of pregnant cows in the development of subclinical ketosis]. Agrarnyj nauchnyj zhurnal. 2016. no. 11. pp. 6-11.
2. Belousov A.I. Ocenka biohimicheskogo profilja korov raznogo napravlenija produktivnosti. [Evaluation of biochemical profile of cows of different productivity lines]. Materialy ІV mezhd. nauch.-praktich. konf. «Zootehnicheskaja nauka: istorija, problemy, perspektivy». [Materials of the IV international scientific-practical conference «Zootechnical science: history, problems, prospects»]. Kamenec-Podolskij, 2014. pp. 282-283.
3. Misajlov V.D., Nezhdanov A.G., Misajlov V.D., Brehov T.P. Problema gestoza u beremennyh zhivotnyh v molochnom skotovodstve i svinovodstve. [The problem of preeclampsia in pregnant animals in dairy cattle and pig breeding]. Veterinarija. 2008. no. 12. pp. 30-33.
4. Panfilova L.S. Sostojanie kislotno-shhelochnogo ravnovesija krovi vo vtorom i tret’em trimestrah neoslozhnennoj beremennosti. [The state of acid-alkaline balance of the blood in se-cond and third trimesters of uncomplicated pregnancy]. Izvestija vysshih uchebnyh zavedenij. Povolzhskij region. Medicinskie nauki. 2014. no. 3. pp. 81-86.
5. Safonov V.A. O metabolicheskom profile vysokoproduktivnyh korov pri beremennosti i besplodii. [About metabolic profile of high productive cows during pregnancy and infertility]. Sel’skohozjajstvennaja biologija. 2008. no. 4. pp. 64-67.
6. Strizhakov A.N., Ignatko I.V., Bajbulatova Sh.Sh., Bogomazova I.M. Antenatal’noe metabolicheskoe i jendokrinnoe programmirovanie pri beremennosti vysokogo riska. [Antenatal metabolic and endocrine programming at high risk pregnancy]. Akusherstvo i ginekologija. 2016. no. 10. pp. 39-47.
7. Delisle H. Programming of chronic disease by impaired fetal nutrition: evidence and complications for policy and intervention strategies. WHO, 2002. 93 p.
8. Donnik I.M., Shkuratova I.A. Osobennosti adaptacii krupnogo rogatogo skota k neblagoprijatnym jekologicheskim faktoram okruzhajushhej sredy. [Features of adaptation of cattle to adverse ecological factors of environment]. Rossijskij zhurnal “Problemy veterinarnoj sanitarii, gigieny i jekologii”. 2009. no. 1. pp. 77-81.
9. Roslyj I.M., Abramov S.V. Biohimicheskie pokazateli krovi pri fiziologicheskoj beremennosti. [Blood biochemical parameters at physiological pregnancy]. Voprosy ginekologii, akusherstva i perinatologii. 2005. no. 4. pp. 7-13.
10. Kelly A., Stanley C. A. Disorders of glutamate metabolism. Mental retardation and developmental disabilities research reviews. 2001. Vol. 7. Р. 287–295.
11. Gromyko E.V. Ocenka sostojanija organizma metodami biohimii. [The assessment of body state by methods of biochemistry]. Jekologicheskij vestnik Severnogo Kavkaza. 2005. no. 2. pp. 80-94.
12. Zhuravleva E.A., Kamenskaja E.N., Bul’ina E.A., Sosnickaja E.V., Kirpich I.A., Chumakova G.N. Rol’ cinka i medi v mikronutrientnom statuse novorozhdennogo. [Role of zinc and copper in micronutrient status of the newborn]. Jekologija cheloveka. 2007. no. 11. pp. 23-28.
13. Wiznitzer A.. Mayer A., Novack V., Sheiner E., Gilutz H. Association of lipid levels during gestation with preeclampsia and gestational diabetes mellitus: a population-based study: American Journal of Obstetrics and Gynecology. 2009. V. 201 (5). no 1. Р. 481.
